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Test. Optimize. Scale.


Dec 30, 2022

My guest is John M. Climaco.  John M. Climaco, JD is the Chairman and CEO of CNS Pharmaceuticals, Inc., (NASDAQ: CNSP) a company Mr. Climaco took public in 2019. CNS is engaged in the research and development of new treatments for malignancies of the brain and central nervous system. The Company's lead candidate is Berubicin, an anthracycline developed at the prestigious University of Texas MD Anderson Cancer Center, the largest cancer research and treatment center in the world. A seasoned entrepreneur, executive, attorney and director, Mr. Climaco has a distinctive record of business successes and more than 19 years of experience managing the operations, strategies and finances of public and private companies. 

As President & CEO of Axial Biotech for over a decade, Mr. Climaco was instrumental in bringing genomic medicine to orthopaedics. Under Mr. Climaco’s leadership, Axial developed and commercialized ScoliScore, a genetic test designed to determine scoliosis prognosis. The Chicago Tribune called ScoliScore “a crystal ball for the spine” and Orthopaedics This Week recognized ScoliScore as the Best New Diagnostics Technology for Spine Care 2010. Leading Axial from inception through to international commercialization, Mr. Climaco raised over $50MM in venture capital, created partnerships with Medtronic, Johnson & Johnson and Smith & Nephew and grew the company’s annual revenue to over $6MM by its second year of commercial operations.

A current or former director of several public companies including Moleculin Biotech (NASDAQ: MBRX), Digirad Corporation (NASDAQ: DRAD), PDI, Inc. (NASDAQ: PDII), PermaFix Environmental Solutions, Inc. (NASDAQ: PESI) and InfuSystem Holdings, Inc. (NASDAQ: INFU), Mr. Climaco has taken a leadership role in complex and difficult turn around efforts. As Chairman of the Strategic Advisory Committees of DRAD and PESI, Mr. Climaco advised management teams on M&A opportunities, restructurings, asset divestments, equity financings and strategic partnerships.

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