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Brain Ponderings podcast with Dr. Mark Mattson

Sep 8, 2026

Measles, Polio, COVID, AIDS, tick-borne encephalitis, Lyme disease, meningitis, yellow fever, and Ebola are examples of diseases that can be fatal and those who survive the infection may have long-term neurological disability resulting from damage to neural circuits caused by the virus or bacteria. Effective vaccines...


Sep 1, 2026

Protein nitrosylation a process by which redox reactions of nitric oxide (NO) and proteins result in covalent modification of the sulfur in the amino acid cysteine resulting in S-nitrosothiol (SNO). In this episode I talk with Scripps Research Professor Stuart Lipton about his research career highlighting the discovery...


Aug 25, 2026

Understanding how diet influences brain health is a very important area of research. During the past two decades there has been an exponential increase in research on the gut microbiome and its roles in health and disease. Diets high in fiber are not only improve gut health but may also be beneficial for other organ...


Aug 12, 2026

The molecular machinery that translates the messenger RNAs into protein is located in ribosomes. Ribosomes are present within neurons in or near synapses, where they are particularly abundant in postsynaptic sites. Evidence suggests that local protein synthesis is required for the ‘strengthening’ (increased size and...


Aug 5, 2026

With the advent of new technological approaches and emerging discoveries has come a growing appreciation for the importance of astrocytes in neuroplasticity. In contrast to the chemical synapses between neurons, astrocytes are directly connected by gap junctions comprised of connexin proteins. In the present episode I...