May 24, 2023
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Diazepam
Valium
Anxiety, pre-op sedation, conscious sedation, treatment of
seizures, insomnia,
management of alcohol withdrawal
Decreases the effects of voltage gated sodium channels to depresses the CNS
Antianxiety agents, anticonvulsants, sedative/hypnotics,
skeletal muscle relax-
ants (centrally acting)
Benzodiazepine
• Contraindicated in hepatic dysfunction
• Use caution with renal impairment
• Can cause dizziness, drowsiness, lethargy, hypotension, physical
depen-
dence, tolerance
• Instruct patient to take as directed
• Caution to avoid alcohol use
• Flumazenil (Romazicon) is the reversal agent