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Wonder Women Entrepreneurs! This is the place to join conversations with thought leaders who amaze, astonish and inspire you. Listen each week as entrepreneur and host Kalika Yap explores the challenges, wisdom and breakthroughs of extraordinary people. (An Entrepreneurs’ Organization production)

Featured guests include:
Lisa Sugar, cofounder of POPSUGAR
Toni Ko, founder of NYX Cosmetics
Devin Alexander, celebrity chef and nutrition expert who appears on "The Biggest Loser"

Learn more about Entrepreneurs’ Organization, the leading peer-to-peer network exclusively for entrepreneurs.

Have a story to tell? Contact us to be a potential guest on the show at podcast@eonetwork.org.

Jul 10, 2026

Dr. Shilpa Sayana is a board-certified internal medicine physician with advanced training in functional and integrative medicine. Born in Zambia and raised in Botswana by physician parents doing foreign aid work, she trained at Yale, the University of Vermont, and UCLA before an HIV fellowship took her to Haiti, Nigeria, and Russia. In this episode, Dr. Sayana explains why normal lab results and optimal health are not the same thing, how high-performing women are often running on depleted hormones and elevated cortisol without knowing it, and what her own health crisis taught her about treating root causes rather than symptoms. Learn how to read your own numbers, ask better questions at your next appointment, and take your health from normal to optimal.

Timestamps: 

00:46 Meet Dr. Shilpa Sayana

02:16 Roots in Botswana

04:00 Switching to Functional Care

06:02 Normal vs Optimal Labs

07:19 Patient Experience Pivot

11:39 Meditation and Stress Reset

14:26 Midlife Health Playbook

18:42 Genetics and Longevity Triangle

23:11 Antibiotics and Gut Health

23:58 Sleep Hacks and Hormones

27:02 Daily Routine and Breathwork

30:23 GLP Drugs and Nutrition

32:41 Motherhood

34:32 Scaling Functional Medicine

36:39 Entrepreneur Stress Mentorship

Links:

Dr. Shilpa’s Website: https://drshilpa.com/

Sayana Medical & Wellness Center: https://www.sayanamedical.com/