May 19, 2023
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Cyclosporine
Sandimmune
Prevention of rejection in transplantation, treatment of severe
RA, management
of ulcerative colitis
Inhibits normal immune response primarily by decreasing the activity of T cells
Immunosuppressant, antirheumatics (DMARD)
Polypeptides (cyclic)
• May cause seizures, tremors, hypertension, hepatotoxicity,
diarrhea, N/V,
gingival hyperplasia
• Increases immune suppression with corticosteroids
• Avoid grapefruit juice while taking this medications
• Assess for signs of organ rejection
• Monitor renal panel, liver enzymes
• Take medication as directed
• Lifelong therapy required for transplant patients
• Instruct pt on how to take blood pressure